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A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Book Lifespan: Why We Age—and Why We Don't Have To Review :

Dr. Sinclair has been doing the podcast rounds and you can learn a lot more from those podcasts about his research than you can from this book. The book itself is full of anecdotes and socio-political-economic idea;, it might be useful as an introduction for those flirting with the idea of life extension, but this book isn't for those who are already interested in it. There's one page in the "Conclusion" section where he mentions what he does which is a 1g NMN, 1g resveratrol, Vitamin D, K2, 83mg aspirin, avoid sugar, bread, pasta, skip one meal a day, get your blood tested, don't smoke, avoid plastic, excessive UV exposure, X-Rays, CT scans, sleep in a cold bedroom, do cold exposure, do exercise.
As one of the pioneers in longevity research, David challenged status quo and demonstrated that nature’s longevity genes seemed to be conserved throughout biology. This is good news, because the changes that occur with aging seem to be correctable later in life. This isn’t another self-help book with meal plans and shopping lists. Instead, it will guide you through the real challenges and progress on our path to not just living longer, but importantly, living healthier.Although this is plenty technical, it’s not an academic tome. Anyone, researcher or layman alike, will be able to follow the story thanks to the inclusion of so many personal accounts and reflections. After finishing, you will have a new perspective and hopefully realize that we have the ability right now to extend healthspan and the very real possibility of extending lifespan in the coming decade.We met in 2009 and he encouraged me to write collaborative journal articles (metabolic winter hypothesis and oxidative priority) and now that work ultimately is the basis for our book, The Healthspan Solution, which focuses more on what we can achieve with diet. It’s been an honor working with him and having a man of his insight as a mentor and friend.

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